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Best Betaine HCl products by transparent scoring (2026)

Single-ingredient products scored by public rules: dose fit, label transparency, data verification, company transparency, third-party testing. Not a measure of efficacy or safety. No paid placement.

Products ranked: 39 · Reference range: 125 – 3,500 mg (source) · Updated 2026-11-01

Reference range: derived from the cited reference values; see the methodology.

Fewer than 20 single-ingredient products exist, so this list also includes combination products; they are marked “combination”.

Dose fit 40 · Label transparency 20 · Data verification 15 · Company transparency 15 · Third-party test 10 (No data (not scored); the other four parts are rescaled from 90 to 100) — Methodology · Betaine HCl →

RankProductPer dayScoreBreakdown
1
tie
Betaine HCL 250 mg
Solaray · US NIH DSLD combination
250 mg100.0
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
1
tie
Betaine HCl Hydrochloric Acid
Swanson · US NIH DSLD combination
650 mg100.0
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
1
tie
Betaine HCl with Pepsin
The Vitamin Shoppe · US NIH DSLD combination
600 mg100.0
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
4
tie
Betaine HCl With Pepsin
Designs for Health · US NIH DSLD combination
750 mg97.8
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
4
tie
Zygest Betaine Hydrochloride 400 mg
Vitamin World · US NIH DSLD
400 mg97.8
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
6
tie
Betaine HCL & Pepsin
Thorne Research · US NIH DSLD combination
1,040 mg94.4
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency10.0/15
Third-party testNo data (not scored)
6
tie
Betaine HCl
Onnit · US NIH DSLD
500 mg94.4
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency10.0/15
Third-party testNo data (not scored)
6
tie
Betaine HCl
Genestra Brands · US NIH DSLD
1,500 mg94.4
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency10.0/15
Third-party testNo data (not scored)
6
tie
Betaine HCl Plus Pepsin
Bluebonnet · US NIH DSLD combination
650 mg94.4
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency10.0/15
Third-party testNo data (not scored)
6
tie
Betaine Hydrochloride
Douglas Laboratories · US NIH DSLD
648 mg94.4
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency10.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL
Good State · US NIH DSLD combination
650 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL
Herbadiet · US NIH DSLD
500 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL
BulkSupplements.com · US NIH DSLD
750 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL
Earthborn Elements · US NIH DSLD
1,680 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL +
KAL · US NIH DSLD combination
328 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL + Pepsin
Nutricost · US NIH DSLD combination
650 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL 1 g Unflavored
Nutricost · US NIH DSLD
3,000 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL 648 mg
Nova Nutritions · US NIH DSLD combination
648 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL and Pepsin
Dr. Mercola · US NIH DSLD combination
1,950 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCL with Pepsin
Herbadiet · US NIH DSLD combination
350 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl
Integrative Therapeutics · US NIH DSLD combination
1,300 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl
Klaire Labs · US NIH DSLD
1,296 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl
Moss Nutrition · US NIH DSLD
750 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl & Pepsin
BioCare · US NIH DSLD combination
400 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl 2600 mg
SuperSmart · US NIH DSLD combination
2,600 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl 750 mg Capsules
BulkSupplements.com · US NIH DSLD
750 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine HCl Capsules 750 mg
BulkSupplements.com · US NIH DSLD
750 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
11
tie
Betaine Hydrochloride
BioAnue · US NIH DSLD
550 mg83.3
Breakdown
Dose fit40.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCL
Higher Nature · US NIH DSLD
300 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCL and Pepsin
Endo-met Laboratories · US NIH DSLD combination
324 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCl 350 mg
Nature's Life · US NIH DSLD combination
350 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCl 400 mg
PhysioLogics · US NIH DSLD
400 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCl 648 mg
NOW · US NIH DSLD combination
648 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine HCl 650 mg
Source Naturals · US NIH DSLD combination
2,600 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
29
tie
Betaine Hydrochloride 600 mg
Nature's Plus · US NIH DSLD
600 mg81.1
Breakdown
Dose fit40.0/40
Label transparency18.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
36 Betaine HCl
Enzymedica Inc. · Health Canada LNHPD combination
650 mg76.7
Breakdown
Dose fit40.0/40
Label transparency14.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
37 High Potency Betaine HCl with Pepsin 650 mg
Solaray · US NIH DSLD above upper reference combination
7,800 mg55.6
Breakdown
Dose fit0.0/40
Label transparency20.0/20
Data verification15/15
Company transparency15.0/15
Third-party testNo data (not scored)
38
tie
Betaine HCl+
Enzyme Science · US NIH DSLD above upper reference
3,900 mg38.9
Breakdown
Dose fit0.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
38
tie
Fast-Acting Betaine HCl
Enzymedica · US NIH DSLD above upper reference
3,900 mg38.9
Breakdown
Dose fit0.0/40
Label transparency20.0/20
Data verification15/15
Company transparency0.0/15
Third-party testNo data (not scored)
For information only; not medical advice. Talk to a doctor or pharmacist before starting or stopping any supplement.
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