Grape seed extract (OPC)
Full ranking Dose tool Products (977)
Key facts
Daily Value (US FDA)—
Tolerable Upper Intake Level (UL)— Reference upper value (cited, not a UL): 475 mg
Median (Per day)31.6 mgP5 5 – P95 200
Products977
Sources: https://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq?atid=grape.seed.extract&lang=eng · Health Canada NNHPD monograph: not to exceed 475 mg grape seed extract/day
Daily dose across products (mg/day)
Reference upper value (cited, not a UL) 475
0.39 mglog scale · n=977450 mg
Label data from official national databases and brand websites, as declared; not lab-verified.
Common questions
Is there an official upper limit for Grape seed extract (OPC)?
No UL has been set. We use a cited reference upper value of 475 mg per day. It comes from the linked study or assessment and is not a regulatory limit. [source]
How much Grape seed extract (OPC) do products usually contain per day?
As of 2026-11-01, 977 products list a comparable daily dose (1,232 dose records; one product can have several). The median is 31.6 mg per day, and 90% of records fall between 5 and 200 mg. Figures come from labels and are not lab-tested. [source]
Top ranked
| Rank | Brand | Product | Per day | Score |
|---|---|---|---|---|
| 1 | International Vitamin Corporation | Grapeseed 100 mg Standardized Extract Softgels | 100 mg | 93.3 |
| 1 | Nutralab Canada Corp. | MapleLife¿ Nutrition and Formula Grape Seed OPC 60 mg Capsules | 60 mg | 93.3 |
| 1 | Integria Healthcare (Australia) Pty Ltd | One-A-Day Grape Seed 19000 | 158 mg | 93.3 |
| 4 | Vitacost | Grape Seed Extract 200 mg | 200 mg | 83.3 |
| 5 | All Natural Nutritional Products (ANNP) Inc. | All Natural, Heart Health, Grape Seed Extract | 200 mg | 76.7 |
For information only; not medical advice. Talk to a doctor or pharmacist before starting or stopping any supplement.