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Other probiotics (Bacillus, Saccharomyces, Streptococcus...)

Most do not settle long term. They interact with the resident microbes as they pass through, and effects depend on the specific strain.

Dose tool Products (218)

Key facts

Daily Value (US FDA)—
Tolerable Upper Intake Level (UL)—
Median (Per day)1,435,000,000 CFUP5 76,000,000 – P95 56,320,000,000
Products218

No authoritative upper value was found. Bounds used to screen out obvious label errors are estimated from the label distribution; see the Methodology.

How it works: Do probiotics stay in the gut for good?

Do probiotics stay in the gut for good? Live microbes (CFU) Survive stomach acid Gut microbiota Host interaction
1/4Probiotics are live microorganisms; labels give the count in CFU (colony-forming units). The count at expiry may be lower than at manufacture.
  1. Probiotics are live microorganisms; labels give the count in CFU (colony-forming units). The count at expiry may be lower than at manufacture.
  2. Some microbes die passing through stomach acid and bile.
  3. Survivors interact with the resident gut microbes; most do not colonise long term.
  4. Possible modes of action include making short-chain fatty acids, competing with pathogens and influencing immune responses; strains differ widely.

Schematic only; positions and scale are not anatomical.

Limits and cautions: Effects are strain-specific; results for one strain cannot be applied to another. People with severely weakened immune systems should ask a doctor first.

Sources: NIH ODS: Probiotics Fact Sheet for Health Professionals

Daily dose across products (CFU/day)

10,000,000 CFUlog scale · n=21869,700,000,000 CFU

Label data from official national databases and brand websites, as declared; not lab-verified.

For information only; not medical advice. Talk to a doctor or pharmacist before starting or stopping any supplement.
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