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Vitamin B9 (folate)

叶酸(folic acid)要在体内转化成四氢叶酸才能用;它提供"一碳单位",参与 DNA 合成。

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Key facts

Daily Value (US FDA)400 mcg
Tolerable Upper Intake Level (UL)1,000 mcg
Median(Per day)400 mcgP5 50 – P95 1,200
Products5,027

Sources: https://ods.od.nih.gov/factsheets/Folate-HealthProfessional/ · FDA DV 400 mcg (https://www.fda.gov/food/nutrition-facts-label/daily-value-nutrition-and-supplement-facts-labels); pre-2016 DV [] (https://www.federalregister.gov/documents/2016/05/27/2016-11867/food-labeling-revision-of-the-nutrition-and-supplement-facts-labels); adult UL 1000 mcg; hard_high=20000 per serving (UL x10 or market maximum), hard_low=DV/1000

How it works:叶酸和"活性叶酸"有什么不同?

叶酸和"活性叶酸"有什么不同? Folic acid / folate Converted to THF DNA / RNA synthesis Homocysteine → methionine
1/4补剂和强化食品中的叶酸(folic acid)比食物中的天然叶酸盐吸收更好,标签用 DFE(膳食叶酸当量)统一换算。
  1. 补剂和强化食品中的叶酸(folic acid)比食物中的天然叶酸盐吸收更好,标签用 DFE(膳食叶酸当量)统一换算。
  2. 在体内转化为四氢叶酸(THF)及其衍生物,例如 5-甲基四氢叶酸。
  3. 四氢叶酸作为一碳单位的载体,参与 DNA 和 RNA 合成,对快速分裂的细胞很重要。
  4. 它和 B12 一起把同型半胱氨酸转化为甲硫氨酸。

Schematic only; positions and scale are not anatomical.

Limits and cautions:成人叶酸(folic acid,补剂与强化食品)UL 为 1,000 mcg/天;高剂量可能掩盖 B12 缺乏。

Sources:NIH ODS: Folate Fact Sheet for Health Professionals

Daily dose across products(mcg/day)

20 mcglog scale · n=5,0275,344 mcg

Label data from official national databases and brand websites, as declared; not lab-verified.

Common forms

FormProductsMedianP5–P95Elemental fraction
Folic acid2992400 mcg50 – 1,000—
L-5-Methyltetrahydrofolate (5-MTHF)1624400 mcg50 – 1,666—
Folinic acid142400 mcg50 – 1,000—

Top ranked

RankBrandProductPer dayScore
1BulletproofMethyl Folate800 mcg90.0
2SwansonFolate 5-Methyltetrahydrofolic Acid 800 mcg800 mcg88.0
3Genestra BrandsActive Folate 10001,000 mcg85.0
3Doctor's BestFully Active Folate 800 mcg800 mcg85.0
3Jarrow FormulasMethyl Folate 400 mcg400 mcg85.0

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For information only; not medical advice. Talk to a doctor or pharmacist before starting or stopping any supplement.
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